ROS-Mediated Autophagy Induced by Dysregulation of Lipid Metabolism Plays a Protective Role in Colorectal Cancer Cells Treated with Gambogic Acid

Gambogic acid (GA), the main active component of gamboge resin, has potent antitumor activity both in vivo and in vitro. However, the underlying molecular mechanisms remain unclear. In this study, we found that GA could initiate autophagy in colorectal cancer cells, and inhibition of the autophagy p...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Zhang, Haiyuan, Lei, Yunlong, Yuan, Ping, Li, Lingjun, Luo, Chao, Gao, Rui, Tian, Jun, Feng, Zuohua, Nice, Edouard C., Sun, Jun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014500/
https://ncbi.nlm.nih.gov/pubmed/24810758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096418
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla