Suppressor of Cytokine Signaling 4 (SOCS4) Protects against Severe Cytokine Storm and Enhances Viral Clearance during Influenza Infection

Suppressor of cytokine signaling (SOCS) proteins are key regulators of innate and adaptive immunity. There is no described biological role for SOCS4, despite broad expression in the hematopoietic system. We demonstrate that mice lacking functional SOCS4 protein rapidly succumb to infection with a pa...

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מידע ביבליוגרפי
Main Authors: Kedzierski, Lukasz, Linossi, Edmond M., Kolesnik, Tatiana B., Day, E. Bridie, Bird, Nicola L., Kile, Benjamin T., Belz, Gabrielle T., Metcalf, Donald, Nicola, Nicos A., Kedzierska, Katherine, Nicholson, Sandra E.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014316/
https://ncbi.nlm.nih.gov/pubmed/24809749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004134
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