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Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines

BACKGROUND: Dioscin, a typical steroid saponin, is isolated from Dioscorea nipponica Makino and Dioscorea zingiberensis Wright. It has estrogenic activity and many studies have also reported that dioscorea plants have an effect in preventing and treating osteoporosis. However, the molecular mechanis...

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מידע ביבליוגרפי
Main Authors: Zhang, Chunfang, Peng, Jinyong, Wu, Shan, Jin, Yue, Xia, Fan, Wang, Changyuan, Liu, Kexin, Sun, Huijun, Liu, Mozhen
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014146/
https://ncbi.nlm.nih.gov/pubmed/24742230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-30
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