Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines

BACKGROUND: Dioscin, a typical steroid saponin, is isolated from Dioscorea nipponica Makino and Dioscorea zingiberensis Wright. It has estrogenic activity and many studies have also reported that dioscorea plants have an effect in preventing and treating osteoporosis. However, the molecular mechanis...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang, Chunfang, Peng, Jinyong, Wu, Shan, Jin, Yue, Xia, Fan, Wang, Changyuan, Liu, Kexin, Sun, Huijun, Liu, Mozhen
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014146/
https://ncbi.nlm.nih.gov/pubmed/24742230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-30
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items