Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration

OBJECTIVE: To test the hypotheses predicted in a hypothetical model of Alzheimer disease (AD) biomarkers that rates of β-amyloid (Aβ) accumulation on PET imaging are not related to hippocampal neurodegeneration whereas rates of neurodegenerative brain atrophy depend on the presence of both amyloid a...

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Main Authors: Jack, Clifford R., Wiste, Heather J., Knopman, David S., Vemuri, Prashanthi, Mielke, Michelle M., Weigand, Stephen D., Senjem, Matthew L., Gunter, Jeffrey L., Lowe, Val, Gregg, Brian E., Pankratz, Vernon S., Petersen, Ronald C.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013810/
https://ncbi.nlm.nih.gov/pubmed/24706010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000386
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