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Site-specific mutagenesis identifies amino acid residues critical in prohormone processing.

Peptide hormones are generally synthesized as inactive higher mol. wt precursors. Processing of the prohormone into biologically active peptides by specific proteolytic cleavages occurs most often at pairs of basic amino acids but also at single arginine residues. To study the role of protein second...

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Bibliografiske detaljer
Main Authors: Gomez, S, Boileau, G, Zollinger, L, Nault, C, Rholam, M, Cohen, P
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC401355/
https://ncbi.nlm.nih.gov/pubmed/2573512
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