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Increased local IgE production induced by common aeroallergens and phenotypic alteration of mast cells in Chinese eosinophilic, but not non-eosinophilic, chronic rhinosinusitis with nasal polyps

BACKGROUND: Eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) display distinct patterns of inflammation. However, the pathogenic mechanisms underlying the heterogeneity of CRSwNP need further investigation. OBJECTIVE: To investigate local immunoglobulin E (IgE) prod...

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Autori principali: Cao, Ping-Ping, Zhang, Ya-Na, Liao, Bo, Ma, Jin, Wang, Bao-Feng, Wang, Heng, Zeng, Ming, Liu, Wei-Hong, Schleimer, Robert P., Liu, Zheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013492/
https://ncbi.nlm.nih.gov/pubmed/24597471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12304
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