Clinical Significance of Cytoplasmic IgE-Positive Mast Cells in Eosinophilic Chronic Rhinosinusitis

Cross-linking of antigen-specific IgE bound to the high-affinity IgE receptor (FcεRI) on the surface of mast cells with multivalent antigens results in the release of mediators and development of type 2 inflammation. FcεRI expression and IgE synthesis are, therefore, critical for type 2 inflammatory...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gion, Yuka, Okano, Mitsuhiro, Koyama, Takahisa, Oura, Tokie, Nishikori, Asami, Orita, Yorihisa, Tachibana, Tomoyasu, Marunaka, Hidenori, Makino, Takuma, Nishizaki, Kazunori, Sato, Yasuharu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084524/
https://ncbi.nlm.nih.gov/pubmed/32155995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051843
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