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Kinetochore microtubule establishment is defective in oocytes from aged mice

Errors in chromosome segregation in mammalian oocytes increase in number with advancing maternal age, and are a major cause of pregnancy loss. Why chromosome segregation errors are more common in oocytes from older females remains poorly understood. In mitosis, accurate chromosome segregation is ena...

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Hlavní autoři: Shomper, Maria, Lappa, Christina, FitzHarris, Greg
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013167/
https://ncbi.nlm.nih.gov/pubmed/24553117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28046
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