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Kinetochore microtubule establishment is defective in oocytes from aged mice
Errors in chromosome segregation in mammalian oocytes increase in number with advancing maternal age, and are a major cause of pregnancy loss. Why chromosome segregation errors are more common in oocytes from older females remains poorly understood. In mitosis, accurate chromosome segregation is ena...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013167/ https://ncbi.nlm.nih.gov/pubmed/24553117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28046 |
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