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Specific Epiblast Loss and Hypoblast Impairment in Cattle Embryos Sensitized to Survival Signalling by Ubiquitous Overexpression of the Proapoptotic Gene BAD

Early embryonic lethality is common, particularly in dairy cattle. We made cattle embryos more sensitive to environmental stressors by raising the threshold of embryo survival signaling required to overcome the deleterious effects of overexpressing the proapoptotic protein BAD. Two primary fibroblas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: van Leeuwen, Jessica, Berg, Debra K., Smith, Craig S., Wells, David N., Pfeffer, Peter L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013130/
https://ncbi.nlm.nih.gov/pubmed/24806443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096843
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