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Piperine Causes G1 Phase Cell Cycle Arrest and Apoptosis in Melanoma Cells through Checkpoint Kinase-1 Activation

In this study, we determined the cytotoxic effects of piperine, a major constituent of black and long pepper in melanoma cells. Piperine treatment inhibited the growth of SK MEL 28 and B16 F0 cells in a dose and time-dependent manner. The growth inhibitory effects of piperine were mediated by cell c...

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Bibliografiske detaljer
Main Authors: Fofaria, Neel M., Kim, Sung-Hoon, Srivastava, Sanjay K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013113/
https://ncbi.nlm.nih.gov/pubmed/24804719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094298
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