A Targeted Next-Generation Sequencing Assay Detects a High Frequency of Therapeutically Targetable Alterations in Primary and Metastatic Breast Cancers: Implications for Clinical Practice

BACKGROUND. The aim of this study was to assess the frequency of potentially actionable genomic alterations in breast cancer that could be targeted with approved agents or investigational drugs in clinical trials using a next-generation sequencing-based genomic profiling assay performed in a Clinica...

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Bibliografiska uppgifter
Huvudupphovsmän: Vasan, Neil, Yelensky, Roman, Wang, Kai, Moulder, Stacy, Dzimitrowicz, Hannah, Avritscher, Rony, Wang, Baliang, Wu, Yun, Cronin, Maureen T., Palmer, Gary, Symmans, W. Fraser, Miller, Vincent A., Stephens, Philip, Pusztai, Lajos
Materialtyp: Artigo
Språk:Inglês
Publicerad: AlphaMed Press 2014
Ämnen:
Breast Cancer
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012963/
https://ncbi.nlm.nih.gov/pubmed/24710307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0377
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