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Activation of human fibroblast-like synoviocytes by uric acid crystals in rheumatoid arthritis
Hyperuricemia-mediated uric acid crystal formation may cause joint inflammation and provoke the destruction of joints through the activation of inflammasome-mediated innate immune responses. However, the immunopathological effects and underlying intracellular regulatory mechanisms of uric acid cryst...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012929/ https://ncbi.nlm.nih.gov/pubmed/21946433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.35 |
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