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Activation of human fibroblast-like synoviocytes by uric acid crystals in rheumatoid arthritis

Hyperuricemia-mediated uric acid crystal formation may cause joint inflammation and provoke the destruction of joints through the activation of inflammasome-mediated innate immune responses. However, the immunopathological effects and underlying intracellular regulatory mechanisms of uric acid cryst...

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Detalhes bibliográficos
Main Authors: Chen, Da P, Wong, Chun K, Tam, Lai S, Li, Edmund K, Lam, Christopher WK
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012929/
https://ncbi.nlm.nih.gov/pubmed/21946433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.35
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