Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes

AIM: To investigate the effect of matrine on proliferation of vascular smooth muscle cells (VSMCs) and elucidate the underlying mechanisms. METHODS: Rat aortic VSMCs were cultured in medium supplemented with 10% fetal bovine serum and treated with various concentrations (0, 5, 10, 15, and 20 mg/L) o...

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Detalhes bibliográficos
Main Authors: Zhu, Ping, Chen, Ji-mei, Chen, Shu-zhen, Zhang, Cheng, Zheng, Shao-yi, Long, Guang, Chen, Ji, Zhou, Zhi-ling, Fan, Rui-xin, Fan, Xiao-ping, Chen, Yan-fang, Zhuang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012916/
https://ncbi.nlm.nih.gov/pubmed/20835268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.145
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