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Parthenolide inhibits proliferation of vascular smooth muscle cells through induction of G(0)/G(1) phase cell cycle arrest

Objective: This study is to determine the effect of the natural product parthenolide, a sesquiterpene lactone isolated from extracts of the herb Tanacetum parthenium, on the proliferation of vascular smooth muscle cells (VSMCs). Methods: Rat aortic VSMCs were isolated and cultured in vitro, and trea...

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Detalhes bibliográficos
Main Authors: Weng, Shao-xiang, Sui, Mei-hua, Chen, Shan, Wang, Jian-an, Xu, Geng, Ma, Ji, Shan, Jiang, Fang, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704971/
https://ncbi.nlm.nih.gov/pubmed/19585671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B0820351
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