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Intracisternal Administration of Tissue Plasminogen Activator Improves Cerebrospinal Fluid Flow and Cortical Perfusion After Subarachnoid Hemorrhage in Mice

Early brain injury (EBI) during the first 72 h after subarachnoid hemorrhage (SAH) is an important determinant of clinical outcome. A hallmark of EBI, global cerebral ischemia, occurs within seconds of SAH and is thought to be related to increased intracranial pressure (ICP). We tested the hypothesi...

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Detalhes bibliográficos
Main Authors: Siler, Dominic A., Gonzalez, Jorge A., Wang, Ruikang K., Cetas, Justin S., Alkayed, Nabil J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012892/
https://ncbi.nlm.nih.gov/pubmed/24526376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-014-0329-y
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