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Subarachnoid hemorrhage and the distribution of drugs delivered into the cerebrospinal fluid

OBJECT: Investigators in experimental and clinical studies have used the intrathecal route to deliver drugs to prevent or treat vasospasm. However, a clot near an artery or arteries after subarachnoid hemorrhage (SAH) may hamper distribution and limit the effects of intrathecally delivered compounds...

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Detalhes bibliográficos
Publicado no:J Neurosurg
Main Authors: Pluta, Ryszard M., Butman, John A., Schatlo, Bawarjan, Johnson, Dennis L., Oldfield, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762042/
https://ncbi.nlm.nih.gov/pubmed/19374502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2009.2.JNS081256
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