Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis

The recognition of β-glucans by dectin-1 has been shown to mediate cell activation, cytokine production and a variety of antifungal responses. Here, we report that the functional activity of dectin-1 in mucosal immunity to Candida albicans is influenced by the genetic background of the host. Dectin-...

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Autori principali: Carvalho, Agostinho, Giovannini, Gloria, De Luca, Antonella, D'Angelo, Carmen, Casagrande, Andrea, Iannitti, Rossana G, Ricci, Giovanni, Cunha, Cristina, Romani, Luigina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012853/
https://ncbi.nlm.nih.gov/pubmed/22543832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.1
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