CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease

Aspergillus fumigatus is a model fungal pathogen and a common cause of infection in individuals with the primary immunodeficiency chronic granulomatous disease (CGD). Although primarily considered a deficiency of innate immunity, CGD is also linked to dysfunctional T cell reactivity. Both CD4(+) and...

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Hlavní autoři: Luca, Antonella De, Iannitti, Rossana G., Bozza, Silvia, Beau, Remi, Casagrande, Andrea, D’Angelo, Carmen, Moretti, Silvia, Cunha, Cristina, Giovannini, Gloria, Massi-Benedetti, Cristina, Carvalho, Agostinho, Boon, Louis, Latgé, Jean-Paul, Romani, Luigina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336987/
https://ncbi.nlm.nih.gov/pubmed/22523066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60862
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