Human CD4(+) effector T lymphocytes generated upon TCR engagement with self-peptides respond defectively to IL-7 in their transition to memory cells

The peripheral repertoire of CD4(+) T lymphocytes contains autoreactive cells that remain tolerant through several mechanisms. However, nonspecific CD4(+) T cells can be activated in physiological conditions as in the course of an ongoing immune response, and their outcome is not yet fully understoo...

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Detalhes bibliográficos
Main Authors: González-Pérez, Gabriela, Segovia, Norma C, Rivas-Carvalho, Amaranta, Reyes, Diana P, Torres-Aguilar, Honorio, Aguilar-Ruiz, Sergio R, Irles, Claudine, Soldevila, Gloria, Sánchez-Torres, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012772/
https://ncbi.nlm.nih.gov/pubmed/23454917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.71
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