TCRζ(dim)lymphocytes define populations of circulating effector cells that migrate to inflamed tissues

The T-cell receptor ζ (TCRζ) chain is a master sensor and regulator of lymphocyte responses. Loss of TCRζ expression has been documented in infectious, inflammatory, and malignant diseases, suggesting that it may serve to limit T-cell reactivity and effector responses at sites of tissue damage. Thes...

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Autores principales: Zhang, Zhuoli, Gorman, Claire L., Vermi, Anna-Chiara, Monaco, Claudia, Foey, Andrew, Owen, Sally, Amjadi, Parisa, Vallance, Alena, McClinton, Catherine, Marelli-Berg, Federica, Isomäki, Pia, Russell, Andrew, Dazzi, Francesco, Vyse, Timothy J., Brennan, Fionula M., Cope, Andrew P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2007
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939810/
https://ncbi.nlm.nih.gov/pubmed/17255353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-064170
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