Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer

Phosphatidylethanolamine N-methyltransferase (PEMT) plays a critical role in breast cancer progression. However, the epigenetic mechanism regulating PEMT transcription remains largely unknown. Here, we show that the first promoter-specific transcript 1 is the major PEMT mRNA species, and methylation...

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Bibliographische Detailangaben
Hauptverfasser: Li, Da, Bi, Fang-Fang, Chen, Na-Na, Cao, Ji-Min, Sun, Wu-Ping, Zhou, Yi-Ming, Cao, Chen, Li, Chun-Yan, Yang, Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012741/
https://ncbi.nlm.nih.gov/pubmed/24675476
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