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Alternating purine-pyrimidine tracts may promote chromosomal translocations seen in a variety of human lymphoid tumours.

Chromosomal abnormalities which are prevalent in human lymphoid tumours are believed to be involved in tumour pathogenesis and their formation may be the result of erroneous activity by the V-D-J recombinase. Frequently, recombinase accessibility is provided by prior transcription of the chromosomal...

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Détails bibliographiques
Auteurs principaux: Boehm, T, Mengle-Gaw, L, Kees, U R, Spurr, N, Lavenir, I, Forster, A, Rabbitts, T H
Format: Artigo
Langue:Inglês
Publié: 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC401268/
https://ncbi.nlm.nih.gov/pubmed/2531086
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