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Alternating purine-pyrimidine tracts may promote chromosomal translocations seen in a variety of human lymphoid tumours.

Chromosomal abnormalities which are prevalent in human lymphoid tumours are believed to be involved in tumour pathogenesis and their formation may be the result of erroneous activity by the V-D-J recombinase. Frequently, recombinase accessibility is provided by prior transcription of the chromosomal...

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Detalhes bibliográficos
Main Authors: Boehm, T, Mengle-Gaw, L, Kees, U R, Spurr, N, Lavenir, I, Forster, A, Rabbitts, T H
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC401268/
https://ncbi.nlm.nih.gov/pubmed/2531086
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