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Germline Mosaicism Does Not Explain the Maternal Age Effect on Trisomy

A variety of hypotheses have been proposed to explain the association between trisomy and increasing maternal age in humans, virtually all of which assume that the underlying mechanisms involve meiotic errors. However, recently Hultén and colleagues [Hulten et al., 2010b] proposed a provocative mode...

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Detalhes bibliográficos
Main Authors: Rowsey, Ross, Kashevarova, Anna, Murdoch, Brenda, Dickenson, Carrie, Woodruff, Tracey, Cheng, Edith, Hunt, Patricia, Hassold, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012642/
https://ncbi.nlm.nih.gov/pubmed/23950106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.36120
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