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Germline Mosaicism Does Not Explain the Maternal Age Effect on Trisomy

A variety of hypotheses have been proposed to explain the association between trisomy and increasing maternal age in humans, virtually all of which assume that the underlying mechanisms involve meiotic errors. However, recently Hultén and colleagues [Hulten et al., 2010b] proposed a provocative mode...

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Autors principals: Rowsey, Ross, Kashevarova, Anna, Murdoch, Brenda, Dickenson, Carrie, Woodruff, Tracey, Cheng, Edith, Hunt, Patricia, Hassold, Terry
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012642/
https://ncbi.nlm.nih.gov/pubmed/23950106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.36120
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