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An enhancer located in a CpG-island 3' to the TCR/CD3-epsilon gene confers T lymphocyte-specificity to its promoter.

The gene encoding the CD3-epsilon chain of the T cell receptor (TCR/CD3) complex is uniquely transcribed in all T lymphocyte lineage cells. The human CD3-epsilon gene, when introduced into the mouse germ line, was expressed in correct tissue-specific fashion. The gene was then screened for T lymphoc...

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Detalles Bibliográficos
Main Authors: Clevers, H, Lonberg, N, Dunlap, S, Lacy, E, Terhorst, C
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC401248/
https://ncbi.nlm.nih.gov/pubmed/2583122
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