An enhancer located in a CpG-island 3' to the TCR/CD3-epsilon gene confers T lymphocyte-specificity to its promoter.

The gene encoding the CD3-epsilon chain of the T cell receptor (TCR/CD3) complex is uniquely transcribed in all T lymphocyte lineage cells. The human CD3-epsilon gene, when introduced into the mouse germ line, was expressed in correct tissue-specific fashion. The gene was then screened for T lymphoc...

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Pubblicato in:	EMBO J
Autori principali:	Clevers, H, Lonberg, N, Dunlap, S, Lacy, E, Terhorst, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08390.x
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