Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.

The structure of the human major histocompatibility complex (MHC) class II molecule HLA-DR1 derived from the human lymphoblastoid cell line LG-2 has been determined in a complex with the Staphylococcus aureus enterotoxin B superantigen. The HLA-DR1 molecule contains a mixture of endogenous peptides...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Jardetzky, T S, Brown, J H, Gorga, J C, Stern, L J, Urban, R G, Strominger, J L, Wiley, D C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8570625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.2.734
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