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Acute myeloid leukemia with t(7;21)(p22;q22) and 5q deletion: a case report and literature review
The gene RUNX1 at chromosome 21q22 encodes the alpha subunit of Core binding factor (CBF), a heterodimeric transcription factor involved in the development of normal hematopoiesis. Translocations of RUNX1 are seen in several types of leukemia with at least 21 identified partner genes. The cryptic t(...
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| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012275/ https://ncbi.nlm.nih.gov/pubmed/24646765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-8 |
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