Upregulation of Gelatinases and Epithelial–Mesenchymal Transition in Small Airway Remodeling Associated with Chronic Exposure to Wood Smoke

BACKGROUND: Peribronchiolar fibrosis is an important feature of small airway remodeling (SAR) in cigarette smoke-induced COPD. The aim of this study was to investigate the role of gelatinases (MMP9, MMP2) and epithelial-mesenchymal transition (EMT) in SAR related to wood smoke (WS) exposure in a rat...

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Main Authors: Zou, Yimin, Li, Shaoxing, Zou, Weifeng, Hu, Guoping, Zhou, Yumin, Peng, Gongyong, He, Fang, Li, Bing, Ran, Pixin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011965/
https://ncbi.nlm.nih.gov/pubmed/24802298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096708
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