Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions

Heat shock cognate protein 70 (Hsc70) acts as a molecular chaperone for the maintenance of intracellular proteins, which allows cancer cells to survive under proteotoxic stress. We attempted to use Hsc70 to identify key molecules in cancer cell survival. Here, we performed mass-spectrometry-based pr...

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Autores principales: Tanaka, Masako, Mun, Saya, Harada, Akihito, Ohkawa, Yasuyuki, Inagaki, Azusa, Sano, Soichi, Takahashi, Katsuyuki, Izumi, Yasukatsu, Osada-Oka, Mayuko, Wanibuchi, Hideki, Yamagata, Masayo, Yukimura, Tokihito, Miura, Katsuyuki, Shiota, Masayuki, Iwao, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011886/
https://ncbi.nlm.nih.gov/pubmed/24801886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096785
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