Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions

Heat shock cognate protein 70 (Hsc70) acts as a molecular chaperone for the maintenance of intracellular proteins, which allows cancer cells to survive under proteotoxic stress. We attempted to use Hsc70 to identify key molecules in cancer cell survival. Here, we performed mass-spectrometry-based pr...

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Hlavní autoři: Tanaka, Masako, Mun, Saya, Harada, Akihito, Ohkawa, Yasuyuki, Inagaki, Azusa, Sano, Soichi, Takahashi, Katsuyuki, Izumi, Yasukatsu, Osada-Oka, Mayuko, Wanibuchi, Hideki, Yamagata, Masayo, Yukimura, Tokihito, Miura, Katsuyuki, Shiota, Masayuki, Iwao, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011886/
https://ncbi.nlm.nih.gov/pubmed/24801886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096785
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