Toll-like receptor alterations in myelodysplastic syndrome

Recent studies have implicated the innate immunity system in the pathogenesis of myelodysplastic syndromes (MDS). Toll-like receptor (TLR) genes encode key innate immunity signal initiators. We recently identified multiple genes, known to be regulated by TLRs, to be overexpressed in MDS bone marrow...

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Autors principals: Wei, Yue, Dimicoli, Sophie, Bueso-Ramos, Carlos, Chen, Rui, Yang, Hui, Neuberg, Donna, Pierce, Sherry, Jia, Yu, Zheng, Hong, Wang, Hui, Wang, Xia, Nguyen, Martin, Wang, Sa A, Ebert, Benjamin, Bejar, Rafael, Levine, Ross, Abdel-Wahab, Omar, Kleppe, Maria, Ganan-Gomez, Irene, Kantarjian, Hagop, Garcia-Manero, Guillermo
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011663/
https://ncbi.nlm.nih.gov/pubmed/23765228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.180
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