Phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in patients with low or intermediate-1 risk myelodysplastic syndrome

A phase II non-randomized single arm trial of oral panobinostat (LBH589) was conducted in patients with low or intermediate-1 risk myelodysplastic syndrome (MDS). The objective of this study was to determine the clinical efficacy, safety, and tolerability of panobinostat in this patient population....

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Autori principali: Dimicoli, Sophie, Jabbour, Elias, Borthakur, Gautam, Kadia, Tapan, Estrov, Zeev, Yang, Hui, Kelly, Mary, Pierce, Sherry, Kantarjian, Hagop, Garcia-Manero, Guillermo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085038/
https://ncbi.nlm.nih.gov/pubmed/22072492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.22198
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