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Post-transcriptional regulation of PTEN dosage by non-coding RNAs
The classic “two-hit” model of tumor suppressor inactivation, originally established by mathematical modeling of cancer incidence, implies that tumorigenesis requires complete loss of function of tumor suppressor genes. While this is true in some tumor types, the exact nature of tumor suppressor der...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011638/ https://ncbi.nlm.nih.gov/pubmed/21045203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.3146pe39 |
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