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Post-transcriptional regulation of PTEN dosage by non-coding RNAs

The classic “two-hit” model of tumor suppressor inactivation, originally established by mathematical modeling of cancer incidence, implies that tumorigenesis requires complete loss of function of tumor suppressor genes. While this is true in some tumor types, the exact nature of tumor suppressor der...

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Bibliografische gegevens
Hoofdauteur: He, Lin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011638/
https://ncbi.nlm.nih.gov/pubmed/21045203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.3146pe39
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