Role of aberrant PI3K pathway activation in gallbladder tumorigenesis

The PI3K/AKT pathway governs a plethora of cellular processes, including cell growth, proliferation, and metabolism, in response to growth factors and cytokines. By acting as a unique lipid phosphatase converting phosphatidylinositol-3,4,5,-trisphosphate (PIP3) to phosphatidylinositol-4,5,-bisphosph...

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Main Authors: Lunardi, Andrea, Webster, Kaitlyn A., Papa, Antonella, Padmani, Bhavik, Clohessy, John G., Bronson, Roderick T., Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
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Priority Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011591/
https://ncbi.nlm.nih.gov/pubmed/24658595
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