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Glucocorticoid receptor binds cooperatively to adjacent recognition sites.

In order to define the mechanism of synergistic induction mediated by multiple glucocorticoid response elements (GRE), the affinity of the glucocorticoid receptor to a single or duplicated GRE was analyzed by gel retardation, nitrocellulose filter binding and by footprinting experiments. Direct meas...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Schmid, W, Strähle, U, Schütz, G, Schmitt, J, Stunnenberg, H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2792086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08350.x
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