Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy

Muscle-invasive bladder cancers (MIBCs) are biologically heterogeneous and have widely variable clinical outcomes and responses to conventional chemotherapy. We discovered 3 molecular subtypes of MIBC that resembled established molecular subtypes of breast cancer. Basal MIBCs shared biomarkers with...

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Hauptverfasser: Choi, Woonyoung, Porten, Sima, Kim, Seungchan, Willis, Daniel, Plimack, Elizabeth R., Hoffman-Censits, Jean, Roth, Beat, Cheng, Tiewei, Tran, Mai, Lee, I-Ling, Melquist, Jonathan, Bondaruk, Jolanta, Majewski, Tadeusz, Zhang, Shizhen, Pretzsch, Shanna, Baggerly, Keith, Siefker-Radtke, Arlene, Czerniak, Bogdan, Dinney, Colin P.N., McConkey, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011497/
https://ncbi.nlm.nih.gov/pubmed/24525232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.01.009
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