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Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo

Alterations in cellular metabolism and bioenergetics are vital for cancer cell growth and motility. Here, the role of the mitochondrial protein voltage-dependent anion channel (VDAC1), a master gatekeeper regulating the flux of metabolites and ions between mitochondria and the cytoplasm, in regulati...

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Detalhes bibliográficos
Main Authors: Arif, Tasleem, Vasilkovsky, Lilia, Refaely, Yael, Konson, Alexander, Shoshan-Barmatz, Varda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011124/
https://ncbi.nlm.nih.gov/pubmed/24781191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.9
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