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Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo

Alterations in cellular metabolism and bioenergetics are vital for cancer cell growth and motility. Here, the role of the mitochondrial protein voltage-dependent anion channel (VDAC1), a master gatekeeper regulating the flux of metabolites and ions between mitochondria and the cytoplasm, in regulati...

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Bibliographic Details
Main Authors: Arif, Tasleem, Vasilkovsky, Lilia, Refaely, Yael, Konson, Alexander, Shoshan-Barmatz, Varda
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011124/
https://ncbi.nlm.nih.gov/pubmed/24781191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.9
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