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Metastasis-associated PRL-3 induces EGFR activation and addiction in cancer cells
Metastasis-associated phosphatase of regenerating liver-3 (PRL-3) has pleiotropic effects in driving cancer progression, yet the signaling mechanisms of PRL-3 are still not fully understood. Here, we provide evidence for PRL-3–induced hyperactivation of EGFR and its downstream signaling cascades in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011027/ https://ncbi.nlm.nih.gov/pubmed/23867504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66824 |
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