Randomised controlled trial. Comparison Of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: Trial design and protocol (CONSTRUCT)

INTRODUCTION: Many patients with ulcerative colitis (UC) present with acute exacerbations needing hospital admission. Treatment includes intravenous steroids but up to 40% of patients do not respond and require emergency colectomy. Mortality following emergency colectomy has fallen, but 10% of patie...

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Detalhes bibliográficos
Main Authors: Seagrove, Anne C, Alam, M Fasihul, Alrubaiy, Laith, Cheung, Wai-Yee, Clement, Clare, Cohen, David, Grey, Michelle, Hilton, Mike, Hutchings, Hayley, Morgan, Jayne, Rapport, Frances, Roberts, Stephen E, Russell, Daphne, Russell, Ian, Thomas, Linzi, Thorne, Kymberley, Watkins, Alan, Williams, John G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Gastroenterology and Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010821/
https://ncbi.nlm.nih.gov/pubmed/24785401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-005091
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