Infliximab versus ciclosporin for steroid-resistant acute severe ulcerative colitis (CONSTRUCT): a mixed methods, open-label, pragmatic randomised trial

BACKGROUND: Infliximab and ciclosporin are of similar efficacy in treating acute severe ulcerative colitis, but there has been no comparative evaluation of their relative clinical effectiveness and cost-effectiveness. METHODS: In this mixed methods, open-label, pragmatic randomised trial, we recruit...

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Pubblicato in:Lancet Gastroenterol Hepatol
Autori principali: Williams, John G, Alam, M Fasih, Alrubaiy, Laith, Arnott, Ian, Clement, Clare, Cohen, David, Gordon, John N, Hawthorne, A Barney, Hilton, Mike, Hutchings, Hayley A, Jawhari, Aida U, Longo, Mirella, Mansfield, John, Morgan, Jayne M, Rapport, Frances, Seagrove, Anne C, Sebastian, Shaji, Shaw, Ian, Travis, Simon P L, Watkins, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994668/
https://ncbi.nlm.nih.gov/pubmed/27595142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2468-1253(16)30003-6
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