REGULATION OF HUMAN PLATELET AGGREGATION BY GENETICALLY MODIFIED PIG ENDOTHELIAL CELLS AND THROMBIN INHIBITION

BACKGROUND: Coagulation disorders remain barriers to successful pig-to-primate organ xenotransplantation. In vitro, we investigated the impact of pig genetic modifications on human platelet aggregation in response to pig aortic endothelial cells (pAEC). METHODS: In comparison to human (h)AEC and wil...

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Detaylı Bibliyografya
Asıl Yazarlar: Iwase, Hayato, Ekser, Burcin, Hara, Hidetaka, Phelps, Carol, Ayares, David, Cooper, David K.C., Ezzelarab, Mohamed B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010578/
https://ncbi.nlm.nih.gov/pubmed/24188473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12073
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