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Leptin-stimulated K(ATP) channel trafficking: A new paradigm for β-cell stimulus-secretion coupling?
Insulin secretion from pancreatic β-cells is initiated by the closure of ATP-sensitive K(+) channels (K(ATP)) in response to high concentrations of glucose, and this action of glucose is counteracted by the hormone leptin, an adipokine that signals through the Ob-R(b) receptor to increase K(ATP) cha...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Landes Bioscience
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010576/ https://ncbi.nlm.nih.gov/pubmed/24213304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.26958 |
| Etiketak: |
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