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Enhancement of the HIF-1α/15-LO/15-HETE Axis Promotes Hypoxia-Induced Endothelial Proliferation in Preeclamptic Pregnancy

Preeclampsia (PE) is an extremely serious condition in pregnant women and the leading cause of maternal and fetal morbidity and mortality. Despite active research, the etiological factors of this disorder remain elusive. The increased release of 15-hydroxyeicosatetraenoic acid (15-HETE) in the place...

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Detalhes bibliográficos
Main Authors: Yuan, Dandan, Ran, Yajuan, Liu, Qian, Zhang, Yanhua, Li, Huiying, Li, Peiling, Zhu, Daling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010521/
https://ncbi.nlm.nih.gov/pubmed/24796548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096510
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